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Protein S Activity, Plasma is a diagnostic test measuring the function of protein S, a critical clotting factor. It helps assess thrombotic risk.
Protein S is a natural anticoagulant protein in blood plasma that regulates clotting. Protein S activity testing measures its functional effectiveness in preventing excessive blood clot formation, aiding in diagnosing conditions like thrombosis or assessing risk factors for clotting disorders. Results are typically reported as a percentage of normal activity, with lower levels indicating potential thrombotic risk. This test is crucial in managing conditions such as deep vein thrombosis, pulmonary embolism, and evaluating patients with suspected clotting disorders.
Second-line testing for diagnosing inherited or acquired protein S deficiency serves as a supplement to initial testing using protein S antigen assay results (free protein S antigen, with or without total protein S antigen assay). This is particularly relevant when assessing patients with a history of venous thromboembolism.
Optical Clot-Based
TBC
Protein S Activity, P
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Plasma Na Cit
TBC
Specimen Type: Platelet-poor plasma
Patient Preparation: The patient must not be receiving Coumadin.
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
0.5 mL
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