HLA-B*5801 Genotype, Allopurinol Hypersensitivity, Varies
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Identifies individuals at risk for severe reactions to allopurinol, enabling personalized treatment to enhance safety and effectiveness.
OVERVIEW
The HLA-B5801 genotype test for allopurinol hypersensitivity identifies individuals at increased risk of severe adverse reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis. This test detects variations in the HLA-B5801 allele, strongly linked to these hypersensitivity reactions. It aids healthcare providers in personalizing treatment by predicting patient responses to allopurinol, enhancing safety and effectiveness.
WHAT IS IT USED FOR?
Detecting individuals at higher risk of severe skin reactions to allopurinol due to the presence of the human leukocyte antigen HLA-B*58:01 allele.
METHOD NAME
Qualitative Allele-Specific Real-Time Polymerase Chain Reaction (PCR)
AVAILABILITY
TBC
REPORTING NAME
HLA-B 5801 Genotype, V
OTHER NAME
- Allopurinol Hypersensitivity Syndrome (AHS)
- Gout
- Lesch-Nyhan Syndrome
- Stevens-Johnson Syndrome
- Toxic Epidermal Necrolysis
- Urate Kidney Stones
- HLA58
- HLAB 5801
- HLA B5801
- B5801
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SPECIMEN TYPE
Whole Blood
SHIPPING INSTRUCTIONS
TBC
SPECIMEN REQUIRED
Collection Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL
Collection Instructions:
- Gently mix the blood by inverting it several times.
- Send the whole blood specimen in its original tube. Do not divide it into smaller portions.
Trust PULSE CLINIC to take care of your health like other 45000 people from over 130 countries. We provide discreet professional service with high privacy. Here to help, not to judge.