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This test is used for diagnosing and managing patients suspected of having irritable bowel syndrome with diarrhea (IBS-D) symptoms related to bile acid malabsorption (BAM). Bile acids, crucial for fat absorption, can lead to diarrhea when not properly absorbed in the colon due to BAM. IBS-D, characterized by various gastrointestinal symptoms, often involves accelerated colonic transit time, with a significant proportion attributed to BAM. While methods for detecting BAM are limited, quantifying fecal bile acids can aid in screening for IBS-D and identifying candidates for bile acid sequestrant therapy, which may alleviate symptoms.
Assistance in assessing individuals with suspected symptoms of irritable bowel syndrome with diarrhea (IBS-D) caused by a deficiency in absorbing bile acids.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
TBC
Bile Acids, Bowel Dysfunc, 48 Hr, F